Multisystem inflammatory syndrome in children (MIS-C) (Podcast Episode 34)

Guest: Nipunie S. Rajapakse, M.D., M.P.H. (@nrajapakseMD)

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)

Pediatric patients who present with fever, lab evidence of inflammation, multisystem involvement, and recent or current SARS-CoV-2 infection fall under the case definition for multisystem inflammatory syndrome in children. They commonly present with persistent fever and gastrointestinal symptoms and concerningly, shock. Why are we seeing disproportionate rates in children of racial and ethnic minorities? Nipunie S. Rajapaske, M.D., M.P.H., concisely covers what's known about this syndrome and the data supporting its emergence as a post-infection complication.

Centers for Disease Control and Prevention health advisory on multisystem inflammatory syndrome in children (MIS-C)
https://emergency.cdc.gov/han/2020/han00432.asp

An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: An observational cohort study
https://doi.org/10.1016/S0140-6736(20)31103-X

AskMayoExpert COVID-19 Navigator resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

This education is supported in part by an independent medical education grant from Pfizer Inc. and is in accordance with ACCME guidelines.

Click here to claim credit and view faculty disclosures. Select Register to begin the credit claim process.

Connect with Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu or on Twitter @MayoMedEd.


Published

August 6, 2020

Created by

Mayo Clinic