The fierce urgency of now – Pursuing a safe and efficacious vaccine (Podcast Episode 32)

Guest: Gregory A. Poland, M.D. (@drgregpoland)

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006)

SARS-CoV-2, as an RNA virus, has marked capacity for mutation and recombination events. How do we build an efficacious and safe vaccine against it? How could we safely speed up development? Is a vaccine neutralizing the spike protein enough? Gregory A. Poland, M.D., gives an update from the front lines of research on vaccine development and ongoing clinical trials. 

Tortoises, hares, and vaccines: A cautionary note for SARS-CoV-2 vaccine development
https://doi.org/10.1016/j.vaccine.2020.04.073

'I Have A Dream' Speech

https://www.npr.org/2010/01/18/122701268/i-have-a-dream-speech-in-its-entirety

Our 'Fierce Urgency of Now' — Secretary Kathleen Sebelius https://obamawhitehouse.archives.gov/blog/2013/08/26/our-fierce-urgency-now

King Legacy: 'Fierce Urgency of Now' Exists Today

https://www.defense.gov/Explore/Features/Story/Article/2059480/king-legacy-fierce-urgency-of-now-exists-today/

AskMayoExpert COVID-19 Navigator resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

This education is supported in part by an independent medical education grant from Pfizer Inc. and is in accordance with ACCME guidelines.

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Published

August 6, 2020

Created by

Mayo Clinic